CELL DAMAGE SHIFTS THE MICRORNA CONTENT OF SMALL EXTRACELLULAR VESICLES INTO A TOLL-LIKE RECEPTOR 7-ACTIVATING CARGO CAPABLE TO PROPAGATE INFLAMMATION AND IMMUNITY

Cell damage shifts the microRNA content of small extracellular vesicles into a Toll-like receptor 7-activating cargo capable to propagate inflammation and immunity

Abstract Background The physiological relevance of cell-to-cell communication mediated by small extracellular vesicle-encapsulated microRNAs (sEV-miRNAs) remains debated because of the limiting representativity of specific miRNAs within the extracellular pool.We hypothesize that sEV-miRNA non-canonical function consisting of the stimulation of Toll

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Anti-SARS-CoV-2, antioxidant and immunomodulatory potential of dietary flavonol quercetin: Focus on molecular targets and clinical efficacy

The current coronavirus disease 2019 (COVID-19) outbreak, caused by the infection of SARS-CoV-2, seems to be a tough global challenge because of Bowling Balls its highly contagious nature and rapid evolution of the virus strain.As no effective clinical drugs are available for the treatment of this disease in the early phase till to date, scientists

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Assessment of Treatment Plan Quality between Flattening Filter and Flattening Filter Free Photon Beam for Carcinoma of the Esophagus with IMRT Technique

Background: As compared to the flattened photon beam, removing the flattening filter (FF) from the head of a gantry decreases the average energy of the photon beam and increases the Honey dipper dose rate, leading to an impact on the quality of treatment plans.Objective: This study aimed to compare the quality of intensity-modulated radiation thera

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Peripheral nerves adjacent to spinal cord injury could help restore sensory motor regeneration in complete paralysis patients

Peripheral nerves adjacent to spinal cord injury could help restore sensory motor neurons regeneration Background and objectives: In people Bowling Balls with spinal cord injury we hypothesize that peripheral nerves in the thoracic segment and accessory nerve and supra scapula nerve branches on the back of the patient can be sacrificed to use them

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